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1

Getting a Grip on Prions: Oligomers, Amyloids, and Pathological Membrane Interactions *

Caughey, Byron, Baron, Gerald S., Chesebro, Bruce, Jeffrey, Martin

Journal:

Annual Review of Biochemistry

Year:

2009

Language:

english

File:

PDF, 1.66 MB

english, 2009

2

P ROTOFIBRILS , P ORES , F IBRILS, AND N EURODEGENERATION : Separating the Responsible Protein Aggregates from The Innocent Bystanders*

Caughey, Byron, Lansbury, Peter T.

Journal:

Annual Review of Neuroscience

Year:

2003

Language:

english

File:

PDF, 493 KB

english, 2003

3

Assessment of Prospective Preventive Therapies for Chronic Wasting Disease in Mule Deer

Wolfe, Lisa L., Kocisko, David A., Caughey, Byron, Miller, Michael W.

Journal:

Journal of Wildlife Diseases

Year:

2012

Language:

english

File:

PDF, 56 KB

english, 2012

4

Melanin or a Melanin-Like Substance Interacts with the N-Terminal Portion of Prion Protein and Inhibits Abnormal Prion Protein Formation in Prion-Infected Cells

Hamanaka, Taichi, Nishizawa, Keiko, Sakasegawa, Yuji, Oguma, Ayumi, Teruya, Kenta, Kurahashi, Hiroshi, Hara, Hideyuki, Sakaguchi, Suehiro, Doh-ura, Katsumi, Caughey, Byron

Journal:

Journal of Virology

Year:

2017

Language:

english

File:

PDF, 8.39 MB

english, 2017

5

High diagnostic value of second generation CSF RT-QuIC across the wide spectrum of CJD prions

Franceschini, Alessia, Baiardi, Simone, Hughson, Andrew G., McKenzie, Neil, Moda, Fabio, Rossi, Marcello, Capellari, Sabina, Green, Alison, Giaccone, Giorgio, Caughey, Byron, Parchi, Piero

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.84 MB

english, 2017

6

Factors That Improve RT-QuIC Detection of Prion Seeding Activity

Orrú, Christina, Hughson, Andrew, Groveman, Bradley, Campbell, Katrina, Anson, Kelsie, Manca, Matteo, Kraus, Allison, Caughey, Byron

Journal:

Year:

2016

Language:

english

File:

PDF, 3.01 MB

english, 2016

7

[Progress in Molecular Biology and Translational Science] Prion Protein Volume 150 || Amplified Detection of Prions and Other Amyloids by RT-QuIC in Diagnostics and the Evaluation of Therapeutics and Disinfectants

Year:

2017

Language:

english

File:

PDF, 416 KB

english, 2017

8

Analysis of the 1H NMR spectra of the carboxylic ionophore narasin A in its Apo and cation-bound forms

Byron W. Caughey, William A. Gibbons, George R. Painter

Journal:

Magnetic Resonance in Chemistry

Year:

1989

Language:

english

File:

PDF, 228 KB

english, 1989

9

The chemistry of scrapie infection: implications of the ‘ice 9’ metaphor

Peter T. Lansbury Jr, Byron Caughey

Journal:

Chemistry & Biology

Year:

1995

Language:

english

File:

PDF, 1.61 MB

english, 1995

10

Aggregates of scrapie-associated prion protein induce the cell-free conversion of protease-sensitive prion protein to the protease-resistant state

Byron Caughey, David A. Kocisko, Gregory J. Raymond, Peter T. Lansbury Jr.

Journal:

Chemistry & Biology

Year:

1995

Language:

english

File:

PDF, 2.85 MB

english, 1995

11

Identification of prion inhibitors by a fluorescence-polarization-based competitive binding assay

David A. Kocisko, Nadine Bertholet, Roger A. Moore, Byron Caughey, Andrew Vaillant

Journal:

Analytical Biochemistry

Year:

2007

Language:

english

File:

PDF, 120 KB

english, 2007

12

Structural Aspects of Congo Red as an Inhibitor of Protease-Resistant Prion Protein Formation

Rémi Demaimay, James Harper, Heather Gordon, Donald Weaver, Bruce Chesebro, Byron Caughey

Journal:

Journal of Neurochemistry

Year:

1998

Language:

english

File:

PDF, 774 KB

english, 1998

13

Conformational change, aggregation and fibril formation induced by detergent treatments of cellular prion protein

Liang-Wen Xiong, Lynne D. Raymond, Stanley F. Hayes, Gregory J. Raymond, Byron Caughey

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 1.10 MB

english, 2001

14

A solid-phase assay for identification of modulators of prion protein interactions

Laura Maxson, Caíne Wong, Lynn M Herrmann, Byron Caughey, Gerald S Baron

Journal:

Analytical Biochemistry

Year:

2003

Language:

english

File:

PDF, 380 KB

english, 2003

15

Metabolic Pools of ATP in Cultured Bovine Adrenal Medullary Chromaffin Cells

James J. Corcoran, Mira Korner, Byron Caughey, Norman Kirshner

Journal:

Journal of Neurochemistry

Year:

1986

Language:

english

File:

PDF, 795 KB

english, 1986

16

Effects of Reserpine and Tetrabenazine on Catecholamine and ATP Storage in Cultured Bovine Adrenal Medullary Chromaffin Cells

Byron Caughey, Norman Kirshner

Journal:

Journal of Neurochemistry

Year:

1987

Language:

english

File:

PDF, 1.10 MB

english, 1987

17

Potent Inhibition of Scrapie-Associated PrP Accumulation by Congo Red

Byron Caughey, Richard E. Race

Journal:

Journal of Neurochemistry

Year:

1992

Language:

english

File:

PDF, 502 KB

english, 1992

18

Cell-free formation of protease-resistant prion protein

Kocisko, David A., Come, Jon H., Priola, Suzette A., Chesebro, Bruce, Raymond, Gregory J., Lansbury, Peter T., Caughey, Byron

Journal:

Year:

1994

File:

PDF, 529 KB

1994

19

10.1038/40876

Caughey, Byron, Raymond, Gregory J., Hope, James, Kocisko, David A., Priola, Suzette A., Raymond, Lynne D., Bossers, Alex, Ironside, James, Will, Robert G., Chen, Shu G., Petersen, Robert B., Gambetti

Journal:

Year:

1997

Language:

english

File:

PDF, 532 KB

english, 1997

20

Prion diseases: A nucleic-acid accomplice?

Caughey, Byron, Kocisko, David A.

Journal:

Year:

2003

Language:

english

File:

PDF, 602 KB

english, 2003

21

10.1038/77476

Journal:

Nature Medicine

Year:

2000

Language:

english

File:

PDF, 210 KB

english, 2000

22

Is PrP the road to ruin?

Barton, Kelly A, Caughey, Byron

Journal:

The EMBO Journal

Year:

2011

Language:

english

File:

PDF, 161 KB

english, 2011

23

The most infectious prion protein particles

Silveira, Jay R., Raymond, Gregory J., Hughson, Andrew G., Race, Richard E., Sim, Valerie L., Hayes, Stanley F., Caughey, Byron

Journal:

Year:

2005

Language:

english

File:

PDF, 442 KB

english, 2005

24

Prions and their partners in crime

Caughey, Byron, Baron, Gerald S.

Journal:

Year:

2006

Language:

english

File:

PDF, 3.21 MB

english, 2006

25

Probing for prions: recognizing misfolded PrP

Journal:

Nature Medicine

Year:

2003

Language:

english

File:

PDF, 200 KB

english, 2003

26

Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking

Atarashi, Ryuichiro, Wilham, Jason M, Christensen, Leah, Hughson, Andrew G, Moore, Roger A, Johnson, Lisa M, Onwubiko, Henry A, Priola, Suzette A, Caughey, Byron

Journal:

Year:

2008

Language:

english

File:

PDF, 383 KB

english, 2008

27

Ultrasensitive detection of scrapie prion protein using seeded conversion of recombinant prion protein

Atarashi, Ryuichiro, Moore, Roger A, Sim, Valerie L, Hughson, Andrew G, Dorward, David W, Onwubiko, Henry A, Priola, Suzette A, Caughey, Byron

Journal:

Year:

2007

Language:

english

File:

PDF, 249 KB

english, 2007

28

Prion diseases — close to effective therapy?

Cashman, Neil R., Caughey, Byron

Journal:

Nature Reviews Drug Discovery

Year:

2004

Language:

english

File:

PDF, 384 KB

english, 2004

29

Structural organization of brain-derived mammalian prions examined by hydrogen-deuterium exchange

Smirnovas, Vytautas, Baron, Gerald S, Offerdahl, Danielle K, Raymond, Gregory J, Caughey, Byron, Surewicz, Witold K

Journal:

Nature Structural and Molecular Biology

Year:

2011

Language:

english

File:

PDF, 494 KB

english, 2011

30

Methods for studying prion protein (PrP) metabolism and the formation of protease-resistant PrP in cell culture and cell-free systems

Byron Caughey, Gregory J. Raymond, Suzette A. Priola, David A. Kocisko, Richard E. Race, Richard A. Bessen, Peter T. Lansbury, Bruce Chesebro

Journal:

Molecular Biotechnology

Year:

1999

Language:

english

File:

PDF, 118 KB

english, 1999

31

Inhibition of scrapie-associated PrP accumulation

Suzette A. Priola, Byron Caughey

Journal:

Molecular Neurobiology

Year:

1994

Language:

english

File:

PDF, 889 KB

english, 1994

32

Scrapie agent reflication without the prion protein?

Bruce Chesebro, Byron Caughey

Journal:

Current Biology

Year:

1993

Language:

english

File:

PDF, 499 KB

english, 1993

33

481: Correlation between urine dipstick measurement and 24-hour urine collections

Shani Delaney, Yvonne Cheng, Avani Lakhani, Byron Taylor, Aaron Caughey

Journal:

American Journal of Obstetrics and Gynecology

Year:

2007

Language:

english

File:

PDF, 50 KB

english, 2007

34

Reaction of complement factors varies with prion strains in vitro and in vivo

Rie Hasebe, Gregory J. Raymond, Motohiro Horiuchi, Byron Caughey

Journal:

Year:

2012

Language:

english

File:

PDF, 1.97 MB

english, 2012

35

The double life of the prion protein

Peter T. Lansbury Jr, Byron Caughey

Journal:

Current Biology

Year:

1996

Language:

english

File:

PDF, 79 KB

english, 1996

36

Prion proteins meet protein quality control

Derek E. Dimcheff, John L. Portis, Byron Caughey

Journal:

Trends in Cell Biology

Year:

2003

Language:

english

File:

PDF, 306 KB

english, 2003

37

Prion protein and the transmissible spongiform encephalopathies

Byron Caughey, Bruce Chesebro

Journal:

Trends in Cell Biology

Year:

1997

Language:

english

File:

PDF, 973 KB

english, 1997

38

Interactions between prion protein isoforms: the kiss of death?

Journal:

Trends in Biochemical Sciences

Year:

2001

Language:

english

File:

PDF, 3.18 MB

english, 2001

39

Prion protein interconversions and the transmissible spongiform encephalopathies

Motohiro Horiuchi, Byron Caughey

Journal:

Year:

1999

Language:

english

File:

PDF, 306 KB

english, 1999

40

Real time quaking-induced conversion analysis of cerebrospinal fluid in sporadic Creutzfeldt–Jakob disease

Lynne I. McGuire, Alexander H. Peden, Christina D. Orrú, Jason M. Wilham, Nigel E. Appleford, Gary Mallinson, Mary Andrews, Mark W. Head, Byron Caughey, Robert G. Will, Richard S. G. Knight, Alison J.

Journal:

Annals of Neurology

Year:

2012

Language:

english

File:

PDF, 390 KB

english, 2012

41

Measurement of Altered Aspartyl Residues in the Scrapie Associated Form of Prion Protein

Darin J. Weber, Philip N. McFadden, Byron Caughey

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 62 KB

english, 1998

42

The role of molecular conformation in ion capture by carboxylic ionophores: a circular dichroism study of narasin A in single-phase solvents and liposomes

Byron Caughey, George R. Painter, Alex F. Drake, William A. Gibbons

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1986

Language:

english

File:

PDF, 613 KB

english, 1986

43

The solvent polarity dependent conformational equilibrium of the carboxylic ionophore narasin: A proton NMR study

Byron Caughey, George Painter, Berton C. Pressman, William A. Gibbons

Journal:

Biochemical and Biophysical Research Communications

Year:

1983

Language:

english

File:

PDF, 1.41 MB

english, 1983

44

Equilibrium cation binding selectivity of the carboxylic ionophore narasin A: A comparison with transport selectivities reported in two biological test systems

Byron Caughey, George R. Painter, William A. Gibbson

Journal:

Biochemical Pharmacology

Year:

1986

Language:

english

File:

PDF, 452 KB

english, 1986

45

Structure of the Flexible Amino-Terminal Domain of Prion Protein Bound to a Sulfated Glycan

Lara M. Taubner, Ewa A. Bienkiewicz, Valérie Copié, Byron Caughey

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.41 MB

english, 2010

46

Comparison of protease-resistant prion protein inhibitors in cell cultures infected with two strains of mouse and sheep scrapie

David A. Kocisko, Abbi L. Engel, Kristin Harbuck, Kevin M. Arnold, Emily A. Olsen, Lynne D. Raymond, Didier Vilette, Byron Caughey

Journal:

Neuroscience Letters

Year:

2005

Language:

english

File:

PDF, 223 KB

english, 2005

47

Ultrastructures and strain comparison of under-glycosylated scrapie prion fibrils

Valerie L. Sim, Byron Caughey

Journal:

Neurobiology of Aging

Year:

2009

Language:

english

File:

PDF, 2.12 MB

english, 2009

48

Prion protein interconversions and TSE diseases

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 173 KB

english, 2000

49

S3-02-03 Prion protein conversions and TSE infections

Byron Caughey, Gerald S. Baron, Ana Cristina Magalhaes, Marco Antonio Prado, David A. Kocisko

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 158 KB

english, 2004

50

Novel therapeutic uses for porphyrins and phthalocyanines in the transmissible spongiform encephalopathies: Commentary

Suzette A Priola, Byron Caughey, Winslow S Caughey

Journal:

Current Opinion in Microbiology

Year:

1999

Language:

english

File:

PDF, 76 KB

english, 1999